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Covalent Modifications of the Bacteriophage Genome Confer a Degree of Resistance to Bacterial CRISPR Systems
ASM Journals
Restriction-modification (R-M) and CRISPR-Cas systems are two well-known defense mechanisms of bacteria. Both recognize and cleave phage DNA...
Il y a 49 mois
Patrick Clark Obituary (2017) - Primos, PA - Delaware County Daily & Sunday Times
Legacy.com
Patrick Mason Clark, age 28 of Aston, a loving husband, son, brother, uncle and friend, passed from this world on October 26, 2017 after a long battle with...
Il y a 37 mois
CRISPR-Mediated Transcriptional Repression in Toxoplasma gondii
ASM Journals
Here, we detail the adaptation of a new set of tools based on CRISPR-Cas9, which allows the targeted downregulation of gene expression in Toxoplasma.
Il y a 18 mois
FIG 2. A 21-channel EEG with the patient awake demonstrates periodic...
ResearchGate
Download scientific diagram | A 21-channel EEG with the patient awake demonstrates periodic sharp-wave complex discharges, which are of greater amplitude...
Il y a 82 mois
Apomorphine Enhances Conditioned Responses Induced by Aversive Stimulation of the Inferior Colliculus
Nature
Recent reports have also demonstrated that aversive stimulation of the IC, at the escape threshold, enhances dopamine (DA) release in the prefrontal cortex.
Il y a 82 mois
CRISPR-Cas systems: new players in gene regulation and bacterial physiology
Frontiers
CRISPR-Cas systems are bacterial defenses against foreign nucleic acids derived from bacteriophages, plasmids or other sources. These systems are targeted...
Il y a 5 mois
Expanding the CRISPR Toolbox in Zebrafish for Studying Development and Disease
Frontiers
In this review, we provide an overview of the increasing number of novel CRISPR-based tools and approaches, including lineage tracing and base editing.
Il y a 5 mois
Editing efficiencies with Cas9 orthologs, Cas12a endonucleases, and temperature in rice
Frontiers
The advent of CRISPR-Cas technology has made it the genome editing tool of choice in all kingdoms of life, including plants, which can have...
Il y a 20 mois
Rapid Evolution of Manifold CRISPR Systems for Plant Genome Editing
Frontiers
Advanced CRISPR-Cas9 based technologies first validated in mammalian cell systems are quickly being adapted for use in plants.
Il y a 10 mois
Synthetic RNAs for Gene Regulation: Design Principles and Computational Tools
Frontiers
The use of synthetic non-coding RNAs for post-transcriptional regulation of gene expression has not only become a standard laboratory tool for gene...
Il y a 5 mois