Hoping to recapture that “Garden State” magic, writer-director Zach Braff goes dark with the addiction film “A Good Person” featuring...
Il y a 21 mois

Patrick Mason Clark, age 28 of Aston, a loving husband, son, brother, uncle and friend, passed from this world on October 26, 2017 after a long battle with...
Il y a 39 mois

Here, we detail the adaptation of a new set of tools based on CRISPR-Cas9, which allows the targeted downregulation of gene expression in Toxoplasma.
Il y a 19 mois

ABSTRACTHigh-risk human papillomaviruses (HPVs), including HPV-16 and HPV-18, are the causative agents of cervical carcinomas and are linked to several...
Il y a 43 mois

Restriction-modification (R-M) and CRISPR-Cas systems are two well-known defense mechanisms of bacteria. Both recognize and cleave phage DNA...
Il y a 50 mois

We report the use of diffusion-weighted MR imaging in the early diagnosis and monitoring of the progression of a histopathologically proved case of sporadic...
Il y a 83 mois

CRISPR-Cas systems are bacterial defenses against foreign nucleic acids derived from bacteriophages, plasmids or other sources. These systems are targeted...
Il y a 6 mois

Introduction: The human immunodeficiency virus type 1 (HIV-1) pandemic has been slowed with the advent of anti-retroviral therapy (ART).
Il y a 12 mois

In this review, we provide an overview of the increasing number of novel CRISPR-based tools and approaches, including lineage tracing and base editing.
Il y a 6 mois

The use of synthetic non-coding RNAs for post-transcriptional regulation of gene expression has not only become a standard laboratory tool for gene...
Il y a 6 mois